SIST ISO/TR 9122-2:1999

Toxicity testing of fire effluents -- Part 2: Guidelines for biological assays to determine the acute inhalation toxicity of fire effluents (basic principles, criteria and methodology)

Name：SIST ISO/TR 9122-2:1999   Standard name：Toxicity testing of fire effluents -- Part 2: Guidelines for biological assays to determine the acute inhalation toxicity of fire effluents (basic principles, criteria and methodology) Standard number：SIST ISO/TR 9122-2:1999   language：English language Release Date：31-Aug-1999   technical committee：POZ - Požarna varnost Drafting committee：   ICS number：13.220.99 - Other standards related to protection against fire

SLOVENSKI STANDARD
SIST ISO/TR 9122-2:1999
01-september-1999
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Toxicity testing of fire effluents -- Part 2: Guidelines for biological assays to determine the
acute inhalation toxicity of fire effluents (basic principles, criteria and methodology)
Essais de toxicité des effluents du feu -- Partie 2: Directives pour les essais biologiques
permettant de déterminer la toxicité aiguë par inhalation des effluents du feu (principes
de base, critères et méthodologie)
Ta slovenski standard je istoveten z: ISO/TR 9122-2:1990
ICS:
13.220.99 Drugi standardi v zvezi z Other standards related to
varstvom pred požarom protection against fire
SIST ISO/TR 9122-2:1999 en
2003-01.Slovenski inštitut za standardizacijo. Razmnoževanje celote ali delov tega standarda ni dovoljeno.

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SIST ISO/TR 9122-2:1999

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SIST ISO/TR 9122-2:1999
TECHNICAL
TR 9122-2
REPORT
First edition
1990-10-15
Toxicity testing of fire effluents -
Part 2:
Guidelines for biological assays to determine the
acute inhalation toxicity of fire effluents (basic
principles, criteria and methodology)
Essais de toxic&? des ef#uents du feu -
Partie 2: Directives pour les essais biologiques permettant de determiner
la toxicit aigui? par inhalation des effluents du feu (principes de base,
wit&-es et m&thodologie)
Reference number
ISWTR 9122-2:1990(E)

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SIST ISO/TR 9122-2:1999
ISO/TR 9122-2:1990(E)
Contents
Page
1 Scope . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .~. 1
2 Definitions . . . . . . . . . . . . . . .-.-.-. 1
3 Principles . . . .I. 3
3.1 Nature of toxic effects . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3
-
3.2 Relevance of animal data to humans . . . . . . . . . . . . . . . . . . .*. 3,
. . 3
3.3 “Classical” inhalation toxicology VS. combustion toxicology
3.4 Determination of qualitative aspects of toxicity (specific
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4
toxicity)
Determination of quantitative aspects of toxicity (toxic potency) 4
3.5
Relative toxicity and its significance 4
3.6 .m.,.,.v.
3.7 Concentration/time/response relationships . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4
3.8 Test concepts ,.-.,. 5
4 Criteria . .l.-. 5
4.1 General criteria . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5
. . . . . . . . . . . . .--. 6
4.2 Fire model
4.3 Analytical measurements . . . . . . . . . . . . . . . . .~. 6
. . . . . . . . . . . . . . . . .-.-.-. 6
4.4 Animals
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .~. 6
4.5 Experimental design
7
4.6 “Exposure-Dose” . .
4.7 Exposure duration . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8
. . . . . . . 8
4.8 Thermal decomposition methods and exposure methods
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8
4.9 Animal exposure modes
8
4.10 Observations and examinations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
4.11 Post mortem examination . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9
. . .---. 9
4.12 Results, data and reporting
6 IS0 1990
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