ISO 17468:2023

Microbiology of the food chain — Technical requirements and guidance on the establishment or revision of a standardized reference method

ISO 17468:2023

Name:ISO 17468:2023   Standard name:Microbiology of the food chain — Technical requirements and guidance on the establishment or revision of a standardized reference method
Standard number:ISO 17468:2023   language:English language
Release Date:12-Nov-2023   technical committee:ISO/TC 34/SC 9 - Microbiology
Drafting committee:ISO/TC 34/SC 9/WG 3 - Method validation   ICS number:07.100.30 - Food microbiology
INTERNATIONAL ISO
STANDARD 17468
Second edition
2023-11
Microbiology of the food chain —
Technical requirements and guidance
on the establishment or revision of a
standardized reference method
Microbiologie de la chaîne alimentaire — Exigences et
recommandations techniques pour le développement ou la révision
d'une méthode de référence normalisée
Reference number
ISO 17468:2023(E)
© ISO 2023

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ISO 17468:2023(E)
COPYRIGHT PROTECTED DOCUMENT
© ISO 2023
All rights reserved. Unless otherwise specified, or required in the context of its implementation, no part of this publication may
be reproduced or utilized otherwise in any form or by any means, electronic or mechanical, including photocopying, or posting on
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ISO copyright office
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Email: [email protected]
Website: www.iso.org
Published in Switzerland
ii
  © ISO 2023 – All rights reserved

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ISO 17468:2023(E)
Contents Page
Foreword .iv
1 Scope . 1
2 Normative references . 1
3 Terms and definitions . 1
4 Technical procedure for standardizing a new reference method.3
4.1 General . 3
4.2 Technical steps . 3
4.2.1 Step 1: Method(s) selection (mandatory) . 3
4.2.2 Step 2: Method(s) optimization (optional) . 4
4.2.3 Step 3: Method(s) evaluation study (recommended) . 4
4.2.4 Step 4: “Real life” study (recommended) . 5
4.2.5 Step 5: Selection of one candidate reference method for further validation
(mandatory) . 5
4.2.6 Step 6: Interlaboratory study (mandatory) . 5
5 Technical procedure for revising a standardized reference method .7
Annex A (informative) Flow chart on technical steps for the establishment or revision of a
standardized reference method.9
Annex B (informative) Guidance on optimization studies to compare two options in the
development of a new standardized reference method or for its revision .10
Bibliography .13
iii
© ISO 2023 – All rights reserved

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ISO 17468:2023(E)
Foreword
ISO (the International Organization for Standardization) is a worldwide federation of national standards
bodies (ISO member bodies). The work of preparing International Standards is normally carried out
through ISO technical committees. Each member body interested in a subject for which a technical
committee has been est
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