ISO 16000-33:2024

Indoor air — Part 33: Determination of phthalates with gas chromatography/mass spectrometry (GC/MS)

ISO 16000-33:2024

Name:ISO 16000-33:2024   Standard name:Indoor air — Part 33: Determination of phthalates with gas chromatography/mass spectrometry (GC/MS)
Standard number:ISO 16000-33:2024   language:English language
Release Date:01-Jul-2024   technical committee:ISO/TC 146/SC 6 - Indoor air
Drafting committee:ISO/TC 146/SC 6 - Indoor air   ICS number:13.040.20 - Ambient atmospheres

International
Standard
ISO 16000-33
Second edition
Indoor air —
2024-07
Part 33:
Determination of phthalates
with gas chromatography/mass
spectrometry (GC/MS)
Air intérieur —
Partie 33: Détermination des phthalates par chromatographie en
phase gazeuse/spectrométrie de masse (CPG/SM)
Reference number
© ISO 2024
All rights reserved. Unless otherwise specified, or required in the context of its implementation, no part of this publication may
be reproduced or utilized otherwise in any form or by any means, electronic or mechanical, including photocopying, or posting on
the internet or an intranet, without prior written permission. Permission can be requested from either ISO at the address below
or ISO’s member body in the country of the requester.
ISO copyright office
CP 401 • Ch. de Blandonnet 8
CH-1214 Vernier, Geneva
Phone: +41 22 749 01 11
Email: [email protected]
Website: www.iso.org
Published in Switzerland
ii
Contents Page
Foreword .v
Introduction .vi
1 Scope . 1
2 Normative references . 1
3 Terms and definitions . 1
4 Abbreviated terms . 2
5 Sampling methods and analytical apparatus. 3
5.1 General .3
5.2 Sampling by adsorption with subsequent thermal desorption .3
5.2.1 Apparatus, operating materials and chemicals .3
5.2.2 Preparation of the thermal desorption tube .4
5.2.3 Sampling .4
5.3 Sampling by adsorption and subsequent solvent extraction .5
5.3.1 Apparatus, operating materials and chemicals .5
5.3.2 Preparation of Florisil and the adsorption tubes .6
5.3.3 Suggestions regarding the application of Florisil .6
5.3.4 Sampling .7
5.3.5 Sample conditioning .7
6 Calibration . 8
6.1 General .8
6.2 Calibration of the thermal desorption method .8
6.3 Calibration of the solvent extraction method .8
7 Identification and quantification . 9
7.1 Mass spectrometric analysis .9
8 Establishment of calibration curves and calculation of the analyte mass. 14
8.1 Establishment of a calibration curve .14
8.2 Calculation of the analyte mass . .14
9 Calculation of indoor air concentrations .15
10 Performance characteristics . 16
10.1 Detection limit .16
10.2 Quantification limit and problems related to blank values .16
10.3 Reproducibility standard deviation and repeatability standard deviation .17
11 Quality assurance .18
11.1 Method verification and determination of blanks .18
11.1.1 General .18
11.1.2 Field blank value of the indoor air .18
11.1.3 Analytical laboratory blank value .18
11.2 Measures for blank value minimization .18
11.3 Documents.19
12 Interferences . 19
Annex A (informative) General information on phthalates .20
Annex B (informative) Sampling by adsorption with ODS solid phase disk or SDB copolymer
cartridge .23
Annex C (informative) Screening phthalates in solvent wipe tests .29
Annex D (informative) Screening phthalates in house dust .32
Annex E (informative) Practical example for the calibration of the thermal desorption method .36

iii
Annex F (informative) Practical example for the calibration of the solvent extraction method
using Florisil .38
Annex G (informative) Practical example for the gas chromatography with thermal desorption .40
Annex H (informative) Practical example for the gas chromatography following solvent
extraction . 41
Annex I (informative) Problems related to the blank values .42
Annex J (informative) Example of sampling protocol documentation .43
Bibliography .44

iv
Foreword
ISO (the International Organization for Standardization) is a worldwide federation of national standards
bodies (ISO member bodies). The work of preparing International Standards is normally carried out through
ISO technical committees. Each member body interested in a subject for which a technical committee
has been established has the right to be represented on that committee. International organizations,
governmental and non-governmental, in liaison with ISO, also take part in the work. ISO collaborates closely
with the International Electrotechnical Commission (IEC) on all matters of electrotechnical standardization.
The procedures used to develop this document and those intended for its further maintenance are described
in the ISO/IEC Directives, Part 1. In particular, the different approval criteria needed for the different types
of ISO document should be noted. This document was drafted in accordance with the editorial rules of the
ISO/IEC Directives, Part 2 (see www.iso.org/directives).
ISO draws attention to the possibility that the implementation of this document may involve the use of (a)
patent(s). ISO takes no position concerning the evidence, validity or applicability of any claimed patent
rights in respect thereof. As of the date of publication of this document, ISO had not received notice of (a)
patent(s) which may be required to implement this document. However, implementers are cautioned that
this may not represent the latest information, which may be obtained from the patent database available at
www.iso.org/patents. ISO shall not be held responsible for identifying any or all such patent rights.
Any trade name used in this document is information given for the convenience of users and does not
constitute an endorsement.
For an explanation of the voluntary nature of standards, the meaning of ISO specific terms and expressions
related to conformity assessment, as well as information about ISO's adherence to the World Trade
Organization (WTO) principles in the Technical Barriers to Trade (TBT), see www.iso.org/iso/foreword.html.
This document was prepared by Technical Committee ISO/TC 146, Air quality, Subcommittee SC 6, Indoor air.
This second edition cancels and replaces the first edition (ISO 16000-33:2017), which has been technically
revised.
The main change is as follows: a description of an adsorbent which can alternatively be used has been added.
A list of all parts in the ISO 16000 series can be found on the ISO website.
Any feedback or questions on this document should be directed to the user’s national standards body. A
complete listing of these bodies can be found at www.iso.org/members.html.

v
Introduction
Different parts of the ISO 16000 series describe the general requirements relating to the measurement of
indoor air pollutants and the important conditions to be observed before or during the sampling of individual
pollutants or groups of pollutants, as well as the measurement procedures themselves.
The definition of indoor environment is given by ISO 16000-1. Dwellings [living rooms, bedrooms, do-it-
yourself (DIY) rooms, sports rooms and cellars, kitchens and bathrooms], workrooms or workplaces in
buildings which are not subject to health and safety inspections with respect to air pollutants (e.g. offices,
salesrooms), public buildings (e.g. restaurants, theatres, cinemas and other meeting rooms) and passenger
cabins of motor vehicles and public transport are among the
...

  • Relates Information
  • ISO 8130-9:1992

    ISO 8130-9:1992 - Coating powders
    09-28
  • EN 352-2:2020/FprA1

    EN 352-2:2021/oprA1:2023
    09-28
  • IEC TS 61158-4:1999

    IEC TS 61158-4:1999 - Digital data communications for measurement and control - Fieldbus for use in industrial control systems - Part 4: Data Link protocol specification Released:3/24/1999 Isbn:2831847656
    09-28
  • HD 566 S1:1990

    HD 566 S1:1998
    09-28
  • ISO 5131:1982/Amd 1:1992

    ISO 5131:1982/Amd 1:1992
    09-28
  • EN 60598-2-22:1990

    EN 60598-2-22:1996
    09-27
  • ISO 8504-2:1992

    ISO 8504-2:1992 - Preparation of steel substrates before application of paints and related products -- Surface preparation methods
    09-27
  • EN 12165:2024

    prEN 12165:2022
    09-27
  • IEC TS 61158-6:1999

    IEC TS 61158-6:1999 - Digital data communications for measurement and control - Fieldbus for use in industrial control systems - Part 6: Application Layer protocol specification Released:3/24/1999 Isbn:2831847613
    09-27
  • ISO 4252:1992

    ISO 4252:1992 - Agricultural tractors -- Operator's workplace, access and exit -- Dimensions
    09-27